KMID : 0978920000010010017
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Korean Journal of Clinical Geriatrics 2000 Volume.1 No. 1 p.17 ~ p.28
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Factors Associated with Functional Dependence in Alzheimer¡¯s Disease
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Cho Choo-Yon
Cho Hang-Seok Cho Kyung-Hee Choi Kyoung-Gyu Oh Hee-Jong Kim Dae-Hyun Jung Seung-Pil Choi Kyu-Dong Lee Hong-Soo Bae Chul-Young
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Abstract
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Backgrond: The pur¥áise of this study was to determine whether common geriatric conditions, family function, and nutritional problems had an independent association ²²th functional dependence beyond the effect of cognitive impairment in ¾Ê patients with Alzheimer¡¯s diseases.
Methods: The ample for this study consisted of 5.¡¯3 in-patients and out-patients of nine hospitals in Korea. All suÀÌects met DSM - IV criteria for dementia and NINCDS- ADRDA criteria for probable Alzheimer¡¯s disease. Among fifty - three patients with probable Alzheimer¡¯s disease, ¿Ül were mil¸çy to moderately impaired and communicable. Chi - square tests were performed to assess bivariate relationships between the selected social and demographic factors, common geriatric conditions, nutritional status, and functional status. Multivariate analyses were done using logistic regression models to adjust for the potentially co nfounding effects of sociodemographic and health variables.
Results: 56.6% of the study JXJpulation was dependent on one or more items in ADLs. The most prevalent items of ADL dependence were bathing (54.7%) and dressing (47.2%) . Subjects with lower education level, poor cognition, and poor nutrition were more likey to be dependent. I¥ñw educational level, JXJOr cognition, and urinary incontinence were associated with the increased risk of ADL dependence. Several conditions are independently associated with the specific items of IADLs. Each item of IADL dependence of the patient has its own set of independent predictors. Some conditions are more universal in independently predicting IADL dependence.
Colcusion: It was found that some common geriatric conditions affecting patients with Alzheimer¡¯ s ÀÌseases appear to have multiple and differential relationships with the specific instrumental activities of daily living (IADLs) dependences. These results have implications for medical care. Preventing one condition may not be sufficient to prevent future IADL dependences since in most cases more than one condition is independently related to each outcome variable. Thus, multiple conditions may need to be managed concurrently if further functional dependence is to be expected.
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KEYWORD
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Alzheimer¡¯s disease, functional dependence, IADLs
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